Title: A Comprehensive Analysis of Postoperative Pain Management in Third Molar Extraction: Dexamethasone's Impact on Pain, Edema, and Trismus (2023)


In the realm of oral surgery, the extraction of impacted third molars poses challenges that extend beyond the surgical procedure itself. This study delves into the nuanced assessment of postoperative outcomes, specifically focusing on the administration of dexamethasone and its effects on pain, edema, and trismus. By scrutinizing the intricacies of pain management, we aim to provide valuable insights into optimizing patient outcomes following third molar extraction.

Methodology: Analyzing Pain Perception

The study employed a rigorous methodology, utilizing the Friedman test to discern any divergence in pain levels between two dexamethasone doses administered postoperatively. Remarkably, no statistically significant differences were observed in pain levels at 24 and 48 hours, underscoring the complexity of postoperative pain assessment.

Discussion: Unraveling the Pain Conundrum

The multifaceted nature of postoperative pain, influenced by variables such as age, gender, anxiety, and surgical complexity, necessitates a meticulous approach to evaluation. Employing the Visual Analog Scale (VAS) and analyzing analgesic consumption, our study aimed to unravel the intricate tapestry of postoperative pain perception. Notably, the study revealed a diminishing trend in pain sensation over the week, irrespective of dexamethasone dosage, challenging conventional expectations.

Edema Assessment: Navigating Three-Dimensional Challenges

Edema, a common sequelae post-third molar extraction, presented challenges in accurate measurement due to its tridimensional nature. Our study, aligning with previous research, showcased a significant reduction in edema with a 4mg dexamethasone dose on the second postoperative day. However, the tripling of the dosage did not yield a discernible difference, suggesting a plateau effect in mitigating edema.

Trismus Dynamics: Beyond Surgical Duration

Trismus, the limitation of mouth opening postoperatively, plays a pivotal role in patient comfort. While our study did not reveal disparities in trismus between dexamethasone dosages, it highlighted a subtle decrease from the first to the second postoperative day. Contrary to edema, trismus dynamics appeared minimally influenced by dexamethasone dosage escalation.

Clinical Implications and Future Considerations

Understanding the impact of dexamethasone on postoperative outcomes provides clinicians with valuable insights for tailored patient care. The absence of significant differences between dosages prompts further exploration into optimal dosage regimens and necessitates consideration of individual patient profiles.


In navigating the intricacies of postoperative pain management, edema, and trismus following third molar extraction, our study sheds light on the nuanced interactions influenced by dexamethasone administration. While no one-size-fits-all approach emerges, the study underscores the need for personalized strategies in enhancing patient recovery. As we delve deeper into the realms of oral surgery, continual exploration and refinement of postoperative protocols remain imperative for advancing patient care and optimizing outcomes.

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